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Cardiovascular & anticoagulation

AF stroke risk and anticoagulation

For confirmed AF. Uses Singapore ACE guidance to calculate stroke risk without a female-sex point and first identifies mechanical valves or moderate–severe mitral stenosis.

Modified CHA₂DS₂-VASc0–8 pointsconfirmed AFSingapore ACE
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01

Confirm applicability first

02

Valvular conditions requiring a separate route

Either condition makes the anticoagulation route independent of this score.

03

Stroke-risk factors

Select factors that are present or previously diagnosed.

Age points are automatic: 65–74 years = 1; ≥75 years = 2.

Primary guidance

Clinical content last reviewed: 29 July 2026

Singapore ACE · oral anticoagulation for AFOriginal CHA₂DS₂-VASc study